Distribution of glycine receptors at central synapses: an immunoelectron microscopy study.
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چکیده
منابع مشابه
Distribution of glycine receptors at central synapses: an immunoelectron microscopy study
The distribution of receptors for a neurotransmitter was investigated cytochemically for the first time in the central nervous system, at synapses established on cells of the ventral horn of the rat cervical spinal cord. Three monoclonal antibodies (mAb's) raised against glycine receptors were used. Immunofluorescent staining already showed discontinuous labeling at the surface of neurons, and ...
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The distribution of glycine receptors on the plasmalemma of the teleost Mauthner cell was examined with light and electron microscopy using monoclonal antibodies raised against the glycine receptors of the rat. These immunoglobulins recognize a peptide of 93 kDa associated with the intracellular side of the receptor complex. With indirect immunofluorescence, labeling appeared as small clusters ...
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The distributions of terminals containing gamma-aminobutyric acid (GABA) and of endings apposed to glycine receptors were investigated cytochemically in the ventral horn of the rat spinal cord. For this purpose, a polyclonal antibody raised to recognize glutamic acid decarboxylase (GAD), a synthetic enzyme for GABA, and three monoclonal antibodies (mAb's) directed against the glycine receptor w...
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Berger, Albert J., Stéphane Dieudonné, and Philippe Ascher. heteromeric NMDA-Rs expressed in Xenopus oocytes and Glycine uptake governs glycine site occupancy at NMDA receptors can reach a few micromolar for other expressed heteromeric of excitatory synapses. J. Neurophysiol. 80: 3336–3340, 1998. At NMDA-Rs (Johnson and Ascher 1992; Mayer et al. 1989; central synapses occupation of glycine bind...
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ژورنال
عنوان ژورنال: The Journal of Cell Biology
سال: 1985
ISSN: 0021-9525,1540-8140
DOI: 10.1083/jcb.101.2.683